Publications

12. Parasar B and Chang PV. "Chemical optogenetic modulation of inflammation and immunity." Chem Sci. 8, 1450-1453 (2017). 

11. Chang PV, Hao L, Offermanns S, Medzhitov R. “The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition.” Proc Natl Acad Sci USA. 111, 2247-2252 (2014).

10. Chang PV, Bertozzi CR. “Imaging beyond the proteome.” Chem Commun. 48, 8864-8879 (2012).

9.  Chang PV, Dube DH, Sletten EM, Bertozzi CR. “A strategy for the selective imaging of glycans using caged metabolic precursors.” J Am Chem Soc. 132, 9516-9518 (2010). 

8.  Chang PV*, Prescher JA*, Sletten EM, Baskin JM, Miller IA, Agard NJ, Lo A, Bertozzi CR. “Copper-free click chemistry in living animals.” Proc Natl Acad Sci USA. 107, 1821-1826 (2010). (*equal contribution)

7.  Chang PV*, Chen X*, Smyrniotis C, Xenakis A, Hu T, Bertozzi CR, Wu P. “Metabolic labeling of sialic acids in living animals with alkynyl sugars.” Angew Chem Int Ed. 48, 4030-4033 (2009).

6.  Guggenheim ER, Xu D, Zhang CX, Chang PV, Lippard SJ. “Photo-affinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA.” ChemBioChem. 10, 141-157 (2009).

5.  Drake PM, Nathan JK, Stock CM, Chang PV, Muench MO, Nakata D, Reader JR, Gip P, Golden KP, Weinhold B, Gerardy-Schahn R, Troy II FA, Bertozzi CR. “Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.” J Immunol. 181, 6850-6858 (2008).

4.  Chang PV, Prescher JA, Hangauer MJ, Bertozzi CR. “Imaging cell surface glycans with bioorthogonal chemical reporters.” J Am Chem Soc. 129, 8400-8401 (2007).

3.  Baskin JM, Prescher JA, Laughlin ST, Agard NJ, Chang PV, Miller IA, Lo A, Codelli JA, Bertozzi CR. “Copper-free click chemistry for dynamic in vivo imaging.” Proc Natl Acad Sci USA. 104, 16793-16797 (2007).

2.  Laughlin ST, Agard NJ, Baskin JM, Carrico IS, Chang PV, Ganguli AS, Hangauer MJ, Lo A, Prescher JA, Bertozzi CR. “Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics.” Methods Enzymol. 415, 230-250 (2006). 

1.  Zhang CX, Chang PV, Lippard SJ. “Identification of nuclear proteins that interact with platinum-modified DNA by photoaffinity labeling.” J Am Chem Soc. 126, 6536-6537 (2004).